Alisson Becker lasted less than 40 minutes of the new Premier League season before limping off with an injury.
The Liverpool shot-stopper slipped after taking a quick free kick and appeared to hold his right knee in pain.
Summer signing Adrian came on to take his place, with the former West Ham No.1 getting a warm reception from the Kop on his debut.
But the injury to Alisson will be a real concern to Jurgen Klopp, who had otherwise watched a flawless first half display from his side.
The Reds took an early lead when Norwich defender Grant Hanley deflected the ball into his own goal.
Divock Origi crossed from the left and when Hanley tried to clear the ball he only directed it past Tim Krul to open the scoring after seven minutes.
VAR was used for the first time in the Premier League to check there were no problems with the goal.
Liverpool doubled their lead with 19 minutes on the clock and it was last season’s top scorer Mohamed Salah who applied the assured finish.
Roberto Firmino slid the ball behind the Norwich defence and Salah steered it past Krul to make it 2-0.
Norwich were not sitting back and had a couple of chances before Marco Stiepermann hit a shot from the edge of the area which Alisson Becker palmed away with 25 minutes gone.
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But the game was less than half an hour old when Liverpool defender Virgil Van Dijk scored the third.
Salah swung in a corner from the left and Van Dijk powered his header past Krul.
And it was four just before the interval as Trent Alexander-Arnold fizzed a delightful pass into the path of Origi, who glanced his header into the Canries’ net.
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